mastodon.me.uk is one of the many independent Mastodon servers you can use to participate in the fediverse.
Open, user-supported, corporation-free social media for the UK.

Administered by:

Server stats:

499
active users

#covid

101 posts81 participants18 posts today

So I'm sitting here thinking about the term "the before times" and how I use that to reference pre-Covid.

But before #Covid, the before times was pre-9/11(2001)

So I was getting ready to toot:

"Age is not how many years you've been alive, but how many 'before times' you've survived" ~Me

Then I realized a case could be made for 1980 being the 'before time' prior to 9/11

THEN my brain went all astrological, because Jupiter conjoins Saturn every 20 years, 🤔

News Release 12-Aug-2025

"What exactly is Long COVID? New UCLA research shows the answer depends on whom you ask: Lack of a standard definition leads to widely varying estimates, complicating care and research"

eurekalert.org/news-releases/1

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2

#Covid

AMELAG-Aggregat, Daten bis 6. August: Steigend.

Grippeweb auch steigende Tendenz.

Die AMELAG-Viruslast-Daten wurden retrospektiv und nicht-linear leicht geändert. Ich ändere die Kalibrierung vorderhand nicht.

Yay. Two negative tests now. One late last night and one this morning.
I also feel a hell of a lot better. I'll take things easy today, but I will need to go back to the lab tomorrow.

Continued thread

4/4

I suggest Congress enact a bill that this level of comprehensive study determining how a virus spreads, be done at the very *moment* there is an #outbreak ... (so that, oh, I don't know, we don't get to the pandemic level??)... of any kind, on animals or humans.

And that it be truly independent

It's like they've been, pardon the pun, playing chicken with our lives with #Covid, and now our foodstock, with #H5N1 and we've gotten lucky so far with our lives on that one.

Arcturus Therapeutics posted a press release that included a section on their pipeline progress yesterday. They are the developers of KOSTAIVE (also known as LUNAR-COV19) , a self-amplifying mRNA #covid #covid19 vaccine.

Arcturus says they have filed for regulatory approval in the UK and expect approval by September. They are also expecting approval in Japan for their 2024-2025 variant update in Q3 or Q4 of 2025. Finally, they say they anticipate filing for US FDA approval sometime in Q3, with approval happening sometime in 2026.

I certainly wish them all the luck in the world with that last one. I'd be more hopeful if the entirety of US healthcare regulatory leadership and some chunk of the American public hadn't completely lost their minds. But here we are.

ir.arcturusrx.com/news-release

From Germany:

"Energy levels decreased on average by ∼2% with each cognitive therapy session (total of 488 sessions, p = 0.0057) and by ∼5% with active therapy sessions"

frontiersin.org/journals/rehab

Screenshot from latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

@covid19 #Coronavirus
#COVID19 #COVID #COVID_19 #COVIDー19 #SARSCoV2 #CovidIsNotOver
@auscovid19 #auscovid19

A recent common cold may nearly halve risk of COVID-19, study suggests

So Covid-Competent folks - this is going to land different in different quarters.

  • The previously evidence-supported paradigm/metaphor "the immune system is a candle not a muscle" might need to be abandoned for a third, more nuanced position[+]
  • Of course there's the need to check the paper itself, and if it's solid, to replicate / validate, but beyond that.
  • Folks with immune dysregulation can't all just catch rhinoviruses all the time to keep the system active.

[+] probably approximately: "microbes vary:

  • some are overwhelmingly beneficial, eg. in our gut;
  • some have mixed costs and benefits like rhinovirus or conditions when they become pathological like candida, and
  • some basically only have costs like influenza(?), SARS1 and SARS2, measles"

re: cidrap.umn.edu/covid-19/recent

www.cidrap.umn.eduA recent common cold may nearly halve risk of COVID-19, study suggestsAmong COVID-infected participants, recent rhinovirus infection was tied to a 9.6-fold lower SARS-CoV-2 viral load, or amount of virus in the body. 

Participants infected with rhinovirus in the previous 30 days were at a 48% lower risk for COVID-19 (adjusted hazard ratio, 0.52). Among COVID-infected participants, recent rhinovirus infection was tied to a 9.6-fold lower SARS-CoV-2 viral load, or amount of virus in the body, an indicator of infection severity.

Rhinovirus infections [...] trigger increased expression of antiviral airway genes,

Higher pre-infection expression of 57 genes, including 24 antiviral defense genes, was linked to a lower SARS-CoV-2 viral load, with rhinovirus infection triggering expression of 22 of the antiviral genes. Children expressed higher levels of the antiviral gene signature and were at a 2.2-fold higher risk for rhinovirus infection than adults.

Sensitivity analyses suggested that, compared with more distant and asymptomatic rhinovirus infection, recent and symptomatic infections were associated with greater reductions in COVID-19 risk.

"Rhinovirus infections, which trigger increased expression of antiviral airway genes, are linked to a lower risk of SARS-CoV-2 infection," the study authors wrote. "Frequent rhinovirus infections may enhance this protective gene profile, partially explaining why children experience milder SARS-CoV-2 infections compared to adults."

from coverage at cidrap.umn.edu/covid-19/recent

www.cidrap.umn.eduA recent common cold may nearly halve risk of COVID-19, study suggestsAmong COVID-infected participants, recent rhinovirus infection was tied to a 9.6-fold lower SARS-CoV-2 viral load, or amount of virus in the body.